Five-Year Risk of Mechanical Ventilation in Community-Dwelling Adults: The Framingham-Intermountain Anticipating Life Support Study.

ABSTRACT:

Objectives

To develop a quantitative tool for identifying outpatients most likely to require life support with mechanical ventilation within 5 years.

Design

Retrospective cohort study.

Setting

Framingham Heart Study (FHS) 1991 to 2009 and Intermountain Healthcare clinics 2008 to 2013.

Participants

FHS participants (n = 3,666; mean age 74; 58% female) in a derivation cohort and Intermountain Healthcare outpatients aged 65 and older (n = 88,302; mean age 73, 57% female) in an external validation cohort.

Measurements

Information on demographic characteristics and comorbidities collected during FHS examinations to derive a 5-year risk score for receiving mechanical ventilation in an intensive care unit, with external validation using administrative data from

SUBMITTER: Walkey AJ 

PROVIDER: S-EPMC5003028 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature