The Negative Relationship between Bilirubin Level and Diabetic Retinopathy: A Meta-Analysis.

ABSTRACT:

Objectives

Findings on the relationship between total bilirubin level (TBL) and diabetic retinopathy (DR) are inconsistent. Thus, we carried out a meta-analysis to investigate the relationship between TBL and the risk of DR.

Methods

Relevant studies were selected from six databases up to 31 May 2016 using a search strategy. The relevant data were extracted from the included studies according to the inclusion and exclusion criteria, and the mean value with standard errors or odds ratio (OR) with 95% confidence intervals (CIs) were calculated. We compared TBL in patients with DR with that in patients with diabetes but without retinopathy (NDR), and analyzed the dose-response relationship between TBL and the risk of DR.

Results

Twenty-four studies were selected in this m

SUBMITTER: Zhu B 

PROVIDER: S-EPMC5003343 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature