Lactation history, serum concentrations of persistent organic pollutants, and maternal risk of diabetes.

ABSTRACT:

Objective

Lactation may help curb diabetes risk and is also known as an excretion route for some environmental pollutants. We evaluated associations of lifetime lactation history with serum concentrations of persistent organic pollutants (POPs) in the National Health and Nutrition Examination Survey 1999-2006, and examined whether potentially diabetogenic POPs account for associations between lactation and diabetes.

Research design and methods

Among 4479 parous women, breastfeeding history was defined as the number of children breastfed ≥1 month. Diabetes was identified by self-report or hemoglobin A1c >6.5%. Twenty-four POPs were measured in serum among subsamples of 668 to 1073 participants.

Results

Compared with women without lactation history, odds ratios (95% con

SUBMITTER: Zong G 

PROVIDER: S-EPMC5003647 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature