Prenatal phthalate exposure and infant size at birth and gestational duration.

ABSTRACT:

Background

Phthalate exposure is widespread. Prior research suggests that prenatal phthalate exposure may influence birth size and gestational duration, but published results have been inconsistent.

Objective

We quantified the relationship between maternal urinary phthalate concentrations and infant birth weight z-scores, length, head circumference, and gestational duration.

Methods

In a cohort of 368 women from the HOME Study, based in Cincinnati, OH, we measured nine phthalate metabolites representing exposure to six parent phthalate diesters in urine collected at approximately 16 and 26 weeks gestation. Infant birth size and gestational duration were abstracted from medical records. We used multivariable linear regression to estimate covariate adjusted associations

SUBMITTER: Shoaff JR 

PROVIDER: S-EPMC5003714 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature