The sexually dimorphic impact of maltreatment on cortical thickness, surface area and gyrification.

ABSTRACT: An extensive literature has detailed how maltreatment experience impacts brain structure in children and adolescents. However, there is a dearth of studies on the influence of maltreatment on surface based indices, and to date no study has investigated how sex influences the impact of maltreatment on cortical thickness, surface area and local gyrification. We investigated sex differences in these measures of cortical structure in a large community sample of children aged 10-14 years (n = 122) comprising 62 children with verified maltreatment experience and 60 matched non-maltreated controls. The maltreated group relative to the controls presented with a pattern of decreased cortical thickness within a region of right anterior cingulate, orbitofrontal cortex and superior frontal gyrus; decr

SUBMITTER: Kelly PA 

PROVIDER: S-EPMC5003912 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature