Robust succinic acid production from crude glycerol using engineered Yarrowia lipolytica.

ABSTRACT:

Background

Integrating waste management with fuels and chemical production is considered to address the food waste problem and oil crisis. Approximately, 600 million tonnes crude glycerol is produced from the biodiesel industry annually, which is a top renewable feedstock for succinic acid production. To meet the increasing demand for succinic acid production, the development of more efficient and cost-effective production methods is urgently needed. Herein, we have proposed a new strategy for integration of both biodiesel and SA production in a biorefinery unit by construction of an aerobic yeast Yarrowia lipolytica with a deletion in the gene coding succinate dehydrogenase subunit 5.

Results

Robust succinic acid production by an engineered yeast Y. lipolytica from crude gl

SUBMITTER: Gao C 

PROVIDER: S-EPMC5004273 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature