Evaluation of Elecsys Syphilis Assay for Routine and Blood Screening and Detection of Early Infection.

ABSTRACT: Treponema pallidum infections can have severe complications if not diagnosed and treated at an early stage. Screening and diagnosis of syphilis require assays with high specificity and sensitivity. The Elecsys Syphilis assay is an automated treponemal immunoassay for the detection of antibodies against T. pallidum The performance of this assay was investigated previously in a multicenter study. The current study expands on that evaluation in a variety of diagnostic settings and patient populations, at seven independent laboratories. The samples included routine diagnostic samples, blood donation samples, samples from patients with confirmed HIV infections, samples from living organ or bone marrow donors, and banked samples, including samples previously confirmed as syphilis positive. This

SUBMITTER: Kremastinou J 

PROVIDER: S-EPMC5005501 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature