Prescription drug monitoring and drug overdose mortality.

ABSTRACT:

Background

Abuse of prescription drugs, particularly opioid analgesics, has become a major source of injury mortality and morbidity in the United States. To prevent the diversion and misuse of controlled substances, many states have implemented prescription drug monitoring programs (PDMPs). This study assessed the impact of state PDMPs on drug overdose mortality.

Methods

We analyzed demographic and drug overdose mortality data for state-quarters with and without PDMPs in 50 states and the District of Columbia during 1999-2008, and estimated adjusted risk ratios (aRRs) and 95% confidence intervals (CIs) of drug overdose mortality associated with the implementation of state PDMPs through multivariable negative bionomial regression modeling.

Results

During the study peri

SUBMITTER: Li G 

PROVIDER: S-EPMC5005551 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature