Polypharmacy Cut-Off for Gait and Cognitive Impairments.

ABSTRACT:

Background

Polypharmacy is a well-established risk factor for falls, and these are one of the major health problems that affect the quality of life as people age. However, the risk of mobility and cognitive impairments consecutive to polypharmacy has been little addressed, despite the association between these adverse outcomes and falls. Moreover, the rare polypharmacy cut-offs were all but one arbitrarily determined.

Objective

Studying relationships between polypharmacy and both mobility and cognitive impairments, and statistically determining a cut-off point in the number of medicinal molecule beyond which polypharmacy has deleterious consequences with respect to mobility and cognitive impairment.

Methods

We enrolled 113 community-dwelling adults aged 55 years and o

SUBMITTER: Langeard A 

PROVIDER: S-EPMC5005954 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature