Anion gap as a prognostic tool for risk stratification in critically ill patients - a systematic review and meta-analysis.

ABSTRACT:

Background

Lactate concentration is a robust predictor of mortality but in many low resource settings facilities for its analysis are not available. Anion gap (AG), calculated from clinical chemistry results, is a marker of metabolic acidosis and may be more easily obtained in such settings. In this systematic review and meta-analysis we investigated whether the AG predicts mortality in adult patients admitted to critical care settings.

Methods

We searched Medline, Embase, Web of Science, Scopus, The Cochrane Library and regional electronic databases from inception until May 2016. Studies conducted in any clinical setting that related AG to in-hospital mortality, in-intensive care unit mortality, 31-day mortality or comparable outcome measures were eligible for inclusion. Me

SUBMITTER: Glasmacher SA 

PROVIDER: S-EPMC5006450 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature