Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia.

ABSTRACT:

Background and purpose

The American Heart Association developed the ideal cardiovascular health (CVH) index as a simple tool to promote CVH; yet, its association with brain atrophy and dementia remains unexamined.

Methods

Our aim was to investigate the prospective association of ideal CVH with vascular brain injury, including the 10-year risks of incident stroke and dementia, as well as cognitive decline and brain atrophy on magnetic resonance imaging, measured for ≈7 years. We studied 2750 stroke- and dementia-free Framingham Heart Study Offspring cohort participants (mean age, 62±9 years; 45% men). Ideal CVH was quantified on a 7-point scale with 1 point awarded for each of the following: nonsmoking status, ideal body mass index, regular physical activity, healthy diet, as

SUBMITTER: Pase MP 

PROVIDER: S-EPMC5006676 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature