Characterization of Ovine Dermal Papilla Cell Aggregation.

ABSTRACT:

Context

The dermal papilla (DP) is a condensation of mesenchymal cells at the proximal end of the hair follicle, which determines hair shaft size and regulates matrix cell proliferation and differentiation. DP cells have the ability to regenerate new hair follicles. These cells tend to aggregate both in vitro and in vivo. This tendency is associated with the ability of papilla cells to induce hair growth. However, human papilla cells lose their hair-inducing activity in later passage number. Ovine DP cells are different from human DP cells since they do not lose their aggregative behavior or hair-inducing activity in culture. Nonetheless, our understanding of ovine DP cells is still limited.

Aim

The aim of this study was to observe the expression of established DP markers in

SUBMITTER: Sari AR 

PROVIDER: S-EPMC5007918 | biostudies-literature | 2016 Jul-Sep

REPOSITORIES: biostudies-literature