Is the increased risk of preterm birth following excision for cervical intraepithelial neoplasia restricted to the first birth post treatment?

ABSTRACT:

Objective

To explore whether the increased risk of preterm birth following treatment for cervical disease is limited to the first birth following colposcopy.

Design

Nested case-control study.

Setting

Twelve NHS hospitals in England.

Population

All nonmultiple births from women selected as cases or controls from a cohort of women with both colposcopy and a hospital birth. Cases had a preterm (20-36 weeks of gestation) birth. Controls had a term birth (38-42 weeks) and no preterm.

Methods

Obstetric, colposcopy and pathology details were obtained.

Main outcome measures

Adjusted odds ratio of preterm birth in first and second or subsequent births following treatment for cervical disease.

Results

A total of 2798 births (1021 preterm) from 2001 w

SUBMITTER: Castanon A 

PROVIDER: S-EPMC5008142 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature