Progression from severe sepsis in pregnancy to death: a UK population-based case-control analysis.

ABSTRACT:

Objective

To identify factors associated with progression from pregnancy-associated severe sepsis to death in the UK.

Design

A population-based case-control analysis using data from the UK Obstetric Surveillance System (UKOSS) and the UK Confidential Enquiry into Maternal Death (CEMD).

Setting

All pregnancy care and death settings in UK hospitals.

Population

All non-influenza sepsis-related maternal deaths (January 2009 to December 2012) were included as cases (n = 43), and all women who survived severe non-influenza sepsis in pregnancy (June 2011 to May 2012) were included as controls (n = 358).

Methods

Cases and controls were identified using the CEMD and UKOSS. Multivariable logistic regression was used to estimate adjusted odds ratios (aOR) with 95%

SUBMITTER: Mohamed-Ahmed O 

PROVIDER: S-EPMC5008196 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature