Association of lifestyle and demographic factors with estrogenic and glucocorticogenic activity in Mexican American women.

ABSTRACT: Breast cancer risk is higher in US-born than in foreign-born Hispanics/Latinas and also increases with greater length of US residency. It is only partially known what factors contribute to these patterns of risk. To gain new insights, we tested the association between lifestyle and demographic variables and breast cancer status, with measures of estrogenic (E) and glucocorticogenic (G) activity in Mexican American women. We used Chemical-Activated LUciferase gene eXpression assays to measure E and G activity in total plasma from 90 Mexican American women, without a history of breast cancer at the time of recruitment, from the San Francisco Bay Area Breast Cancer Study. We tested associations of nativity, lifestyle and sociodemographic factors with E and G activity using linear regression m

SUBMITTER: Fejerman L 

PROVIDER: S-EPMC5008251 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature