Cryptococcal meningitis complicating sarcoidosis.

ABSTRACT:

Background

Cryptococcal meningitis is an uncommon but severe complication of sarcoidosis.

Methods

We present 2 patients with cryptococcal meningitis complicating sarcoidosis and compared findings with 38 cases reported in the literature.

Results

When analyzing our patients and 38 cases reported in the literature, we found that median age of sarcoidosis patients with cryptococcal meningitis was 39 years (range 30-48); 27 of 33 reported cases (82%) had a history of sarcoidosis. Only 16 of 40 patients (40%) received immunomodulating therapy at the time of diagnosis of cryptococcal meningitis. The diagnosis of cryptococcal meningitis was delayed in 17 of 40 patients (43%), mainly because of the initial suspicion of neurosarcoidosis. Cerebrospinal fluid (CSF) examination s

SUBMITTER: Leonhard SE 

PROVIDER: S-EPMC5008555 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature