Potential role of microRNA-126 in the diagnosis of cancers: A systematic review and meta-analysis.

ABSTRACT:

Background

Cancer has become a major public concern all over the world and early diagnosis of cancer is of great benefit for treatment and prognosis. Several studies have investigated the association between abnormal circulating microRNA-126 (miR-126) expression and the risk of various cancers, but the results are inconsistent. Therefore, this meta-analysis was carried out to assess the potential diagnostic value of miR-126 for cancer.

Methods

Relevant studies were searched from PubMed, Embase, and Web of Science and we calculated the pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the summary receiver operator characteristic curve (AUC) to assess the diagnostic value of miR-126 fo

SUBMITTER: Yan J 

PROVIDER: S-EPMC5008569 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature