Functional connectome fingerprinting: identifying individuals using patterns of brain connectivity.

ABSTRACT: Functional magnetic resonance imaging (fMRI) studies typically collapse data from many subjects, but brain functional organization varies between individuals. Here we establish that this individual variability is both robust and reliable, using data from the Human Connectome Project to demonstrate that functional connectivity profiles act as a 'fingerprint' that can accurately identify subjects from a large group. Identification was successful across scan sessions and even between task and rest conditions, indicating that an individual's connectivity profile is intrinsic, and can be used to distinguish that individual regardless of how the brain is engaged during imaging. Characteristic connectivity patterns were distributed throughout the brain, but the frontoparietal network emerged as m

SUBMITTER: Finn ES 

PROVIDER: S-EPMC5008686 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature