Long term cause specific mortality among 34 489 five year survivors of childhood cancer in Great Britain: population based cohort study.

ABSTRACT:

Objective

 To determine whether modern treatments for cancer are associated with a net increased or decreased risk of death from neoplastic and non-neoplastic causes among survivors of childhood cancer.

Design

 Population based cohort study.

Setting

 British Childhood Cancer Survivor Study.

Participants

 Nationwide population based cohort of 34 489 five year survivors of childhood cancer with a diagnosis from 1940 to 2006 and followed up until 28 February 2014.

Main outcome measures

 Cause specific standardised mortality ratios and absolute excess risks are reported. Multivariable Poisson regression models were utilised to evaluate the simultaneous effect of risk factors. Likelihood ratio tests were used to test for heterogeneity or trend.

Results

SUBMITTER: Fidler MM 

PROVIDER: S-EPMC5008696 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature