Serum Leptin Is a Biomarker of Malnutrition in Decompensated Cirrhosis.

ABSTRACT:

Background and aims

Malnutrition is a leading cause of morbidity and mortality in cirrhosis. There is no consensus as to the optimal approach for identifying malnutrition in end-stage liver disease. The aim of this study was to measure biochemical, serologic, hormonal, radiographic, and anthropometric features in a cohort of hospitalized cirrhotic patients to characterize biomarkers for identification of malnutrition.

Design

In this prospective observational cohort study, 52 hospitalized cirrhotic patients were classified as malnourished (42.3%) or nourished (57.7%) based on mid-arm muscle circumference < 23 cm and dominant handgrip strength < 30 kg. Anthropometric measurements were obtained. Appetite was assessed using the Simplified Nutrition Appetite Questionnaire (SNAQ)

SUBMITTER: Rachakonda V 

PROVIDER: S-EPMC5008824 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature