Helicobacter pylori in children with asthmatic conditions at school age, and their mothers.

ABSTRACT:

Background

Helicobacter pylori prevalence in Western countries has been declining simultaneously with increases in childhood asthma and allergic diseases; prior studies have linked these phenomena.

Aims

To examine the association between H. pylori colonisation in children and risk of asthma and related conditions at school age. We secondly examined additional effects of maternal H. pylori status by pairing with children's status.

Methods

This study was embedded in a multi-ethnic population-based cohort in Rotterdam, The Netherlands. We measured anti-H. pylori and anti-CagA antibodies in serum of children obtained at age 6 years, and of their mothers obtained during midpregnancy. Asthma or related conditions were reported for children at age 6 years. We used multivaria

SUBMITTER: den Hollander WJ 

PROVIDER: S-EPMC5009009 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature