Guidelines to electrode positioning for human and animal electrical impedance myography research.

ABSTRACT: The positioning of electrodes in electrical impedance myography (EIM) is critical for accurately assessing disease progression and effectiveness of treatment. In human and animal trials for neuromuscular disorders, inconsistent electrode positioning adds errors to the muscle impedance. Despite its importance, how the reproducibility of resistance and reactance, the two parameters that define EIM, are affected by changes in electrode positioning remains unknown. In this paper, we present a novel approach founded on biophysical principles to study the reproducibility of resistance and reactance to electrode misplacements. The analytical framework presented allows the user to quantify a priori the effect on the muscle resistance and reactance using only one parameter: the uncertainty placing

SUBMITTER: Sanchez B 

PROVIDER: S-EPMC5009322 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature