Glucose Absorption by the Bacillary Band of Trichuris muris.

ABSTRACT:

Background

A common characteristic of Trichuris spp. infections in humans and animals is the variable but low efficacy of single-dose benzimidazoles currently used in mass drug administration programmes against human trichuriasis. The bacillary band, a specialised morphological structure of Trichuris spp., as well as the unique partly intracellular habitat of adult Trichuris spp. may affect drug absorption and perhaps contribute to the low drug accumulation in the worm. However, the exact function of the bacillary band is still unknown.

Methodology

We studied the dependency of adult Trichuris muris on glucose and/or amino acids for survival in vitro and the absorptive function of the bacillary band. The viability of the worms was evaluated using a motility scale from 0 to 3,

SUBMITTER: Hansen TV 

PROVIDER: S-EPMC5010283 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature