Detection of Hepatitis E Virus Genotype 1 Among Blood Donors From Southwest of Iran.

ABSTRACT:

Background

Infection with hepatitis E virus (HEV) is endemic in developing countries and reveals significant regional differences. Several studies have reported virus transmission via blood transfusion. To date, however, no cases of HEV RNA detection in blood donors have been reported from Iran.

Objectives

The aim of this study was to determine the presence of HEV RNA in plasma samples of blood donors referred to a blood transfusion center in Shiraz in the southwest of Iran. The HEV genotypes were also investigated using nucleotide sequencing.

Patients and methods

Blood samples were collected from 700 blood donors who were referred to Fars blood transfusion organization from January to March 2014. Plasma samples were screened for the presence of HEV IgG and IgM antibo

SUBMITTER: Parsa R 

PROVIDER: S-EPMC5011639 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature