The cnidarian Hydractinia echinata employs canonical and highly adapted histones to pack its DNA.

ABSTRACT:

Background

Cnidarians are a group of early branching animals including corals, jellyfish and hydroids that are renowned for their high regenerative ability, growth plasticity and longevity. Because cnidarian genomes are conventional in terms of protein-coding genes, their remarkable features are likely a consequence of epigenetic regulation. To facilitate epigenetics research in cnidarians, we analysed the histone complement of the cnidarian model organism Hydractinia echinata using phylogenomics, proteomics, transcriptomics and mRNA in situ hybridisations.

Results

We find that the Hydractinia genome encodes 19 histones and analyse their spatial expression patterns, genomic loci and replication-dependency. Alongside core and other replication-independent histone variants, we

SUBMITTER: Torok A 

PROVIDER: S-EPMC5011920 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature