Multicenter Evaluation of Geometric Accuracy of MRI Protocols Used in Experimental Stroke.

ABSTRACT: It has recently been suggested that multicenter preclinical stroke studies should be carried out to improve translation from bench to bedside, but the accuracy of magnetic resonance imaging (MRI) scanners routinely used in experimental stroke has not yet been evaluated. We aimed to assess and compare geometric accuracy of preclinical scanners and examine the longitudinal stability of one scanner using a simple quality assurance (QA) protocol. Six 7 Tesla animal scanners across six different preclinical imaging centers throughout Europe were used to scan a small structural phantom and estimate linear scaling errors in all orthogonal directions and volumetric errors. Between-scanner imaging consisted of a standard sequence and each center's preferred sequence for the assessment of infarct si

SUBMITTER: Milidonis X 

PROVIDER: S-EPMC5014410 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature