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Hemodynamic and Autonomic Response to Different Salt Intakes in Normotensive Individuals.


ABSTRACT: Even if sodium sensitivity represents a risk factor at any blood pressure (BP) level, limited evidence is available that it may influence cardiovascular control in normotensives, particularly in white individuals. Therefore, the aim of the study was to investigate whether sodium sensitivity alters hemodynamic or autonomic responses to salt in normotensives. We evaluated the Sodium-Sensitivity Index (SS-Index) in 71 white normotensives after 5 days of high- and low-sodium diets. We measured BP continuously at the end of each period, estimating hemodynamic indices from BP waveform analysis, and autonomic indices from heart rate (HR) and BP variability. According to the SS-Index distribution, we defined 1 sodium-sensitive group (SS, with SS-Index >15 mm Hg/[mmol·day]), 1 sodium-resistant grou

SUBMITTER: Castiglioni P 

PROVIDER: S-EPMC5015293 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature