Epidemiologic contributions to recent cancer trends among HIV-infected people in the United States.

ABSTRACT:

Objective

HIV-infected people have elevated risk for some cancers. Changing incidence of these cancers over time may reflect changes in three factors: HIV population demographic structure (e.g. age distribution), general population (background) cancer rates, and HIV-associated relative risks. We assessed the contributions of these factors to time trends for 10 cancers during 1996-2010.

Design

Population-based registry linkage study.

Methods

We applied Poisson models to data from the U.S. HIV/AIDS Cancer Match Study to estimate annual percentage changes (APCs) in incidence rates of AIDS-defining cancers [ADCs: Kaposi sarcoma, non-Hodgkin lymphoma (NHL), and cervical cancer] and seven non-AIDS-defining cancers (NADCs). We evaluated HIV-infected cancer trends with and wi

SUBMITTER: Robbins HA 

PROVIDER: S-EPMC5015650 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature