F18-FDG-PET for recurrent differentiated thyroid cancer: a systematic meta-analysis.

ABSTRACT:

Background

Positron emission tomography (PET) with fluor-18-deoxy-glucose (FDG) is widely used for diagnosing recurrent or metastatic disease in patients with differentiated thyroid cancer (DTC).

Purpose

To assess the diagnostic accuracy of FDG-PET for DTC in patients after ablative therapy.

Material and methods

A systematic search was conducted in Medline/PubMed, EMBASE, Cochrane Library, Web of Science, and Open Grey looking for all English-language original articles on the performance of FDG-PET in series of at least 20 patients with DTC having undergone ablative therapy including total thyroidectomy. Diagnostic performance measures were pooled using Reitsma's bivariate model.

Results

Thirty-four publications between 1996 and 2014 met the inclusion criteria.

SUBMITTER: Haslerud T 

PROVIDER: S-EPMC5015757 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature