A comparative analysis of Patient-Reported Expanded Disability Status Scale tools.

ABSTRACT:

Background

Patient-Reported Expanded Disability Status Scale (PREDSS) tools are an attractive alternative to the Expanded Disability Status Scale (EDSS) during long term or geographically challenging studies, or in pressured clinical service environments.

Objectives

Because the studies reporting these tools have used different metrics to compare the PREDSS and EDSS, we undertook an individual patient data level analysis of all available tools.

Methods

Spearman's rho and the Bland-Altman method were used to assess correlation and agreement respectively.

Results

A systematic search for validated PREDSS tools covering the full EDSS range identified eight such tools. Individual patient data were available for five PREDSS tools. Excellent correlation was observed be

SUBMITTER: Collins CD 

PROVIDER: S-EPMC5015760 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature