Serum Amylase Levels in Relation to Islet β Cell Function in Patients with Early Type 2 Diabetes.

ABSTRACT:

Objective

The insulin-pancreatic acinar axis may play a major role in pancreatic function. Amylase is an exocrine enzyme that is produced by pancreatic acinar cells, and low serum amylase levels may be associated with endocrine diseases, such as metabolic syndrome and diabetes. We hypothesized that low serum amylase levels may be associated with impaired islet β cell function in type 2 diabetes. Therefore, we investigated the relationship between the serum amylase levels and islet β cell function in patients with early type 2 diabetes.

Methods

The cross-sectional study recruited 2327 patients with a mean of 1.71±1.62 years since their diagnosis of type 2 diabetes, and all participants were treated with lifestyle intervention alone. Serum amylase levels, the 75-g oral glucose

SUBMITTER: Zhuang L 

PROVIDER: S-EPMC5015989 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature