The interplay of vaccination and vector control on small dengue networks.

ABSTRACT: Dengue fever is a major public health issue affecting billions of people in over 100 countries across the globe. This challenge is growing as the invasive mosquito vectors, Aedes aegypti and Aedes albopictus, expand their distributions and increase their population sizes. Hence there is an increasing need to devise effective control methods that can contain dengue outbreaks. Here we construct an epidemiological model for virus transmission between vectors and hosts on a network of host populations distributed among city and town patches, and investigate disease control through vaccination and vector control using variants of the sterile insect technique (SIT). Analysis of the basic reproductive number and simulations indicate that host movement across this small network influences the seve

SUBMITTER: Hendron RS 

PROVIDER: S-EPMC5016021 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature