Analysis of Body Mass Index and Mortality in Patients With Colorectal Cancer Using Causal Diagrams.

ABSTRACT:

Importance

Physicians and investigators have sought to determine the relationship between body mass index (BMI [calculated as weight in kilograms divided by height in meters squared]) and colorectal cancer (CRC) outcomes, but methodologic limitations including sampling selection bias, reverse causality, and collider bias have prevented the ability to draw definitive conclusions.

Objective

To evaluate the association of BMI at the time of, and following, colorectal cancer (CRC) diagnosis with mortality in a complete population using causal diagrams.

Design, setting, and participants

This retrospective observational study with prospectively collected data included a cohort of 3408 men and women, ages 18 to 80 years, from the Kaiser Permanente Northern California populat

SUBMITTER: Kroenke CH 

PROVIDER: S-EPMC5016213 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature