The Quest for Anti-inflammatory and Anti-infective Biomaterials in Clinical Translation.

ABSTRACT: Biomaterials are now being used or evaluated clinically as implants to supplement the severe shortage of available human donor organs. To date, however, such implants have mainly been developed as scaffolds to promote the regeneration of failing organs due to old age or congenital malformations. In the real world, however, infection or immunological issues often compromise patients. For example, bacterial and viral infections can result in uncontrolled immunopathological damage and lead to organ failure. Hence, there is a need for biomaterials and implants that not only promote regeneration but also address issues that are specific to compromised patients, such as infection and inflammation. Different strategies are needed to address the regeneration of organs that have been damaged by inf

SUBMITTER: Griffith M 

PROVIDER: S-EPMC5016531 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature