Mechanotransduction-Induced Lipid Production System with High Robustness and Controllability for Microalgae.

ABSTRACT: Microalgae lipids are a promising energy source, but current biochemical methods of lipid-inductions such as nitrogen deprivation have low process robustness and controllability. Recently, use of mechanotransduction based membrane distortion by applying compression stress in a 2D-microsystem was suggested as a way to overcome these limitations of biochemical induction. However, reproduction in large numbers of cells without cell death has been difficult to overcome because compression for direct membrane distortion reduces culture volume and leads to cell death due to nutrient deprivation. In this study, a mechanotransduction-induced lipid production (MDLP) system that redirects elastic microbeads to induce membrane distortion of microalgae with alleviating cell death was developed. This s

SUBMITTER: Cho MK 

PROVIDER: S-EPMC5016897 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature