Sleep Duration and Cancer in the NIH-AARP Diet and Health Study Cohort.

ABSTRACT:

Background

Very few studies have examined sleep duration in relation to cancer incidence with the exception of breast cancer.

Methods

We assessed the associations between sleep duration and incidences of total and 18 site-specific cancers in the NIH-AARP Health and Diet Study cohort, with 173,327 men and 123,858 women aged 51-72 years at baseline. Self-reported sleep duration categories were assessed via questionnaire. We used multivariable Cox proportional hazards regression to estimate hazard ratios (HR) and 95% confidence intervals (CI), using 7-8 hours/night as the reference.

Results

We observed a significantly increased risk of stomach cancer among male short sleepers (multivariable HR5-6 vs. 7-8 hours = 1.29; 95%CI: 1.05, 1.59; Ptrend = 0.03). We also observed s

SUBMITTER: Gu F 

PROVIDER: S-EPMC5017779 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature