Efficient Integration of Coupled Electrical-Chemical Systems in Multiscale Neuronal Simulations.

ABSTRACT: Multiscale modeling and simulations in neuroscience is gaining scientific attention due to its growing importance and unexplored capabilities. For instance, it can help to acquire better understanding of biological phenomena that have important features at multiple scales of time and space. This includes synaptic plasticity, memory formation and modulation, homeostasis. There are several ways to organize multiscale simulations depending on the scientific problem and the system to be modeled. One of the possibilities is to simulate different components of a multiscale system simultaneously and exchange data when required. The latter may become a challenging task for several reasons. First, the components of a multiscale system usually span different spatial and temporal scales, such that ri

SUBMITTER: Brocke E 

PROVIDER: S-EPMC5018489 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature