Synaptic organization of striate cortex projections in the tree shrew: A comparison of the claustrum and dorsal thalamus.

ABSTRACT: The tree shrew (Tupaia belangeri) striate cortex is reciprocally connected with the dorsal lateral geniculate nucleus (dLGN), the ventral pulvinar nucleus (Pv), and the claustrum. In the Pv or the dLGN, striate cortex projections are thought to either strongly "drive", or more subtly "modulate" activity patterns respectively. To provide clues to the function of the claustrum, we compare the synaptic arrangements of striate cortex projections to the dLGN, Pv, and claustrum, using anterograde tracing and electron microscopy. Tissue was additionally stained with antibodies against γ-aminobutyric acid (GABA) to identify GABAergic interneurons and non-GABAergic projection cells. The striate cortex terminals were largest in the Pv (0.94 ± 0.08 μm² ), intermediate in the claustrum (0.3

SUBMITTER: Day-Brown JD 

PROVIDER: S-EPMC5018911 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature