Proper Control of Caulobacter crescentus Cell Surface Adhesion Requires the General Protein Chaperone DnaK.

ABSTRACT:

Unlabelled

Growth in a surface-attached bacterial community, or biofilm, confers a number of advantages. However, as a biofilm matures, high-density growth imposes stresses on individual cells, and it can become less advantageous for progeny to remain in the community. Thus, bacteria employ a variety of mechanisms to control attachment to and dispersal from surfaces in response to the state of the environment. The freshwater oligotroph Caulobacter crescentus can elaborate a polysaccharide-rich polar organelle, known as the holdfast, which enables permanent surface attachment. Holdfast development is strongly inhibited by the small protein HfiA; mechanisms that control HfiA levels in the cell are not well understood. We have discovered a connection between the essential general prot

SUBMITTER: Eaton DS 

PROVIDER: S-EPMC5019048 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature