Mitochondrial DNA variation, genetic structure and demographic history of Iranian populations.

ABSTRACT: In order to survey the evolutionary history and impact of historical events on the genetic structure of Iranian people, the HV2 region of 141 mtDNA sequences related to six Iranian populations were analyzed. Slight and non-significant F_ST distances among the Central-western Persian speaking populations of Iran testify to the common origin of these populations from one proto-population. Mismatch distribution suggests that this proto-Iranian population started to colonize Iran about 30000 years ago which is almost consistent with the timing of arrival and colonization of western Asia by the anatomically modern human. Star-like haplotype network structures, significant and negative Tajima's D (D=-2.08, P<0.05) and unimodal mismatch distributions support the genetic effects of this

SUBMITTER: Zarei F 

PROVIDER: S-EPMC5019220 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature