Palladium-Catalyzed Oxidative Synthesis of α-Acetoxylated Enones from Alkynes.

ABSTRACT: We report a palladium-catalyzed oxidative functionalization of alkynes to generate α-acetoxylated enones in one step. A range of functional groups are well-tolerated in this reaction. Mechanistic studies, including the use of (18) O-labeled DMSO, revealed that the ketone oxygen atom in the product originates from DMSO.

SUBMITTER: Jiang T 

PROVIDER: S-EPMC5021131 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature