Genetic structure of phenotypic robustness in the collaborative cross mouse diallel panel.

ABSTRACT: Developmental stability and canalization describe the ability of developmental systems to minimize phenotypic variation in the face of stochastic micro-environmental effects, genetic variation and environmental influences. Canalization is the ability to minimize the effects of genetic or environmental effects, whereas developmental stability is the ability to minimize the effects of micro-environmental effects within individuals. Despite much attention, the mechanisms that underlie these two components of phenotypic robustness remain unknown. We investigated the genetic structure of phenotypic robustness in the collaborative cross (CC) mouse reference population. We analysed the magnitude of fluctuating asymmetry (FA) and among-individual variation of cranial shape in reciprocal crosses am

SUBMITTER: Gonzalez PN 

PROVIDER: S-EPMC5021570 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature