Hyperglycaemia and risk of adverse perinatal outcomes: systematic review and meta-analysis.

ABSTRACT:

Objectives

 To assess the association between maternal glucose concentrations and adverse perinatal outcomes in women without gestational or existing diabetes and to determine whether clear thresholds for identifying women at risk of perinatal outcomes can be identified.

Design

 Systematic review and meta-analysis of prospective cohort studies and control arms of randomised trials.

Data sources

 Databases including Medline and Embase were searched up to October 2014 and combined with individual participant data from two additional birth cohorts.

Eligibility criteria for selecting studies

 Studies including pregnant women with oral glucose tolerance (OGTT) or challenge (OGCT) test results, with data on at least one adverse perinatal outcome.

Appraisal and dat

SUBMITTER: Farrar D 

PROVIDER: S-EPMC5021824 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature