Decreased LIPF expression is correlated with DGKA and predicts poor outcome of gastric cancer.

ABSTRACT: Gastric cancer (GC) is a common and deadly digestive tract tumor worldwide. Unfortunately, diagnosis of GC is usually confused and misleading because of atypical symptoms or incomplete complaints. Accordingly, exploring gene expression profile and identifying genes with analogical variance trend will bring new perspective into the diagnosis and treatment of GC. Herein, a RNA‑Seq dataset from Caucasian GC and their matched non‑cancerous samples [Gene Expression Omnibus (GEO): SRP049809] and datasets from four microarrays constituted with tumor and non‑tumor tissues (GEO: GSE13911, GSE19826, GSE29272, GSE33335) were analyzed to explore the differentially expressed genes (DGEs). As a result, we identified a core set of 373 DGEs. Among these genes, we found that most downregulated genes were r

SUBMITTER: Kong Y 

PROVIDER: S-EPMC5022960 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature