Vitamin D Status and Rates of Cognitive Decline in a Multiethnic Cohort of Older Adults.

ABSTRACT:

Importance

Vitamin D (VitD) deficiency is associated with brain structural abnormalities, cognitive decline, and incident dementia.

Objective

To assess associations between VitD status and trajectories of change in subdomains of cognitive function in a cohort of ethnically diverse older adults.

Design, setting, and participants

Longitudinal multiethnic cohort study of 382 participants in an outpatient clinic enrolled between February 2002 and August 2010 with baseline assessment and yearly follow-up visits. Serum 25-hydroxyvitamin D (25-OHD) was measured, with VitD status defined as the following: deficient, less than 12 ng/mL (to convert to nanomoles per liter, multiply by 2.496); insufficient, 12 to less than 20 ng/mL; adequate, 20 to less than 50 ng/mL; or high, 50

SUBMITTER: Miller JW 

PROVIDER: S-EPMC5023277 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature