Ontology highlight
ABSTRACT:
SUBMITTER: Tanihara F
PROVIDER: S-EPMC5023319 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Science advances 20160914 9
Genetically modified pigs for biomedical applications have been mainly generated using the somatic cell nuclear transfer technique; however, this approach requires complex micromanipulation techniques and sometimes increases the risks of both prenatal and postnatal death by faulty epigenetic reprogramming of a donor somatic cell nucleus. As a result, the production of genetically modified pigs has not been widely applied. We provide a simple method for CRISPR (clustered regularly interspaced sho ...[more]