Localized, gradient-reversed ultrafast z-spectroscopy in vivo at 7T.

ABSTRACT:

Purpose

To collect ultrafast z-spectra in vivo in situations where voxel homogeneity cannot be assured.

Theory

Saturating in the presence of a gradient encodes the frequency offset spatially across a voxel. This encoding can be resolved by applying a similar gradient during readout. Acquiring additional scans with the gradient polarity reversed effectively mirrors the spatial locations of the frequency offsets so that the same physical location of a positive offset in the original scan will contribute a negative offset in the gradient-reversed scan.

Methods

Gradient-reversed ultrafast z-spectroscopy (GRUFZS) was implemented and tested in a modified, localized PRESS sequence at 7T. Lysine phantoms were scanned at various concentrations and compared with coventionally-a

SUBMITTER: Wilson NE 

PROVIDER: S-EPMC5023501 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature