Long-term results of fertility-sparing treatment compared with standard radical surgery for early-stage epithelial ovarian cancer.

ABSTRACT:

Background

The objective of this study is to evaluate the safety of fertility-sparing surgery (FSS) for early-stage epithelial ovarian cancer (EOC).

Methods

A retrospective analysis was performed to identify patients treated for early-stage EOC and to compare the clinical outcomes of patients treated with FSS and radical surgery (RS).

Results

A total of 1031 patients were treated at two Institutions, 242 with FSS (group A) and 789 with RS (group B). Median duration of follow-up was 11.9 years. At univariate analyses, FSS was associated with decreased risk of relapse (P=0.002) and of tumour-related death (P=0.001). Multivariate analysis did not confirm the independent positive role of FSS neither on relapse-free interval (RFI) nor on cancer-specific survival (CSS). Tum

SUBMITTER: Fruscio R 

PROVIDER: S-EPMC5023783 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature