A systematic review and meta-analysis including GRADE qualification of the risk of surgical site infections after prophylactic negative pressure wound therapy compared with conventional dressings in clean and contaminated surgery.

ABSTRACT:

Objective

Systematically review and Grading of Recommendations Assessment, Development, and Evaluation (GRADE) studies on prophylactic negative pressure wound therapy (pNPWT) to prevent surgical site infections (SSIs).

Introduction

pNPWT has been suggested as a new method to prevent wound complications, specifically SSIs, by its application on closed incisional wounds.

Methods

This review was conducted as part of the development of the Global Guidelines for prevention of SSIs commissioned by World Health Organization in Geneva. PubMed, Embase, CENTRAL, CINAHL, and the World Health Organization database between January 1, 1990 and October 7, 2015 were searched. Inclusion criteria were randomized controlled trials and observational studies comparing pNPWT with conventio

SUBMITTER: De Vries FEE 

PROVIDER: S-EPMC5023882 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature