Short- and Long-Term Reproducibility of Intrahepatic Lipid Quantification by 1H-MR Spectroscopy and CT in Obesity.

ABSTRACT:

Objective

This study aimed to assess short- and long-term reproducibility of intrahepatic lipid (IHL) quantification by proton magnetic resonance spectroscopy (H-MRS) and computed tomography (CT).

Methods

Sixteen obese subjects underwent H-MRS using a single-voxel point-resolved single-voxel spectroscopy sequence at 3 T and noncontrast single-slice CT of the liver. Measurements were repeated after 6 weeks and 6 months. Clinical parameters (weight, activity, serum lipids) were collected. Short-term (baseline to 6 weeks) and long-term (baseline to 6 months) reproducibility of IHL was assessed by coefficient of variance (CV), SD, and intraclass correlation coefficient (ICC).

Results

Short-term reproducibility and long-term reproducibility of H-MRS were as follows: CV, 5.

SUBMITTER: Dichtel LE 

PROVIDER: S-EPMC5025332 | biostudies-literature | 2016 Sep-Oct

REPOSITORIES: biostudies-literature